Natural Growth Hormone Therapies: The Differences between Sermorelin, GHRP-2 and, GHRP-6

Confused between Sermorelin, GHRP-2, and GHRP-6? Check this post to find out.

There are 2 types of HGH therapy – synthetic Human Growth Hormone Therapy and Natural Human Growth Hormone Therapy.

Human Growth Hormone (HGH) Therapy is an introduction of a combination of 191 amino acids – a complex protein molecule – to the body in a single peptide chain, mimicking the functions of the natural growth hormone in the body.

Natural Human Growth Hormone Therapy (secretagogues) is a method of providing natural amino acid chains in the body that helps stimulate the pituitary gland to release growth hormone naturally.

What is a Secretagogue in growth hormone?

Growth Hormone Secretagogues (GHS) are synthetic peptidyl and non-peptidyl molecules, binding the specific receptors, known as GHS-Rs, in the pituitary gland and hypothalamus. The role of secretagogues on growth hormone is it stimulates the pituitary gland to produce growth hormone in a natural form. These GHS are readily available in only a few pharmacies.

Sermorelin, GHRP-2, and GHRP-6

There are three HGH therapy options – Sermorelin, GHRP-2, and GHRP-6; each one has pros and cons and essential roles to act.

Sermorelin

The Sermorelin is used to treat growth problems (more on children than adults) due to deficiency in growth hormone. It helps stimulate the pituitary gland to secrete natural growth hormone.

The Sermorelin is a synthetic amino acid peptide that contains the first 29 of the amino acids, which makes up the Human Growth-Releasing Hormone or GHRH. It directly stimulates the pituitary gland to secrete more natural growth hormones. Also, the drug is recommended to adults who want to slow down the unwanted effects of aging.

However, Sermorelin is a controlled drug, which means you need a prescription from your doctor for you to purchase and use it.

Pros:

Increased lean body mass

  • Helps in fat reduction
  • Improved energy, strength, vitality, and endurance
  • Fast healing
  • Improved cardiovascular health and immune function
  • Quality sleep
  • Improved bone density
  • Improve skin quality

Cons:

The cons of Sermorelin are outweighed by the pros. However, during the administration of the drug, the patient may experience pain, swelling, and redness of the injection site.

GHRP-2

The GHRP-2 or Growth Hormone Releasing Peptide 2 is a synthetic agonist of Ghrelin. Ghrelin is a 28-amino acid peptide that also helps stimulate the pituitary gland to release growth hormone naturally.

Pros:

  • Increase in lean body mass
  • Helps in body fat reduction
  • Improved energy, strength, vitality, and endurance
  • Improved vision and brain cell aging
  • Fast healing
  • Improved cardiovascular health and immune function
  • Quality sleep
  • Improved bone density
  • Improve skin quality

Cons:

Due to Ghrelin – a ‘hunger hormone’ – individuals undergoing the therapy are found to gain more weight than lose it. For this reason, undergoing this therapy while you are losing weight may not be helpful.

GHRP-6

Growth Hormone-Releasing Peptide-6, also known as Growth Hormone-Releasing Hexapeptide, is a synthetic amino acid peptide that consists of 6 amino acids. The hormone sends a signal to the body to secrete GH while suppressing Somatostatin, a hormone that suppresses the secretion of GH.

Pros:

  • Increase of lean-body mass through promoting Ghrelin
  • Body fat reduction
  • Improved energy, strength, vitality, and endurance
  • Quality sleep
  • Improved memory
  • Prevents injuries
  • Lowers the blood sugar

Cons:

The GHRP-6 also promotes Ghrelin for muscle bulking; however, improper use of the drug may result to increase weight and other health problems.

Final Thoughts

Although the Sermorelin, GHRP-2, and GHRP-6 have similarities, the efficiency will depend on the purpose, your current health condition, and the dose. For this reason, you need to consult an experienced physician when you are considering undergoing Natural Growth Hormone Therapy. Besides, all three therapies require a doctor’s recommendation and prescription.

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